We describe two customers with cutaneous angiomyolipoma associated with the earlobe, all of which were medically misdiagnosed and mistreated as epidermoid cysts, to emphasize the necessity to think about an easy spectral range of differential diagnoses when assessing any nodular or cystic tumefaction for the ear. We provide a comprehensive literature analysis about this cutaneous entity.Pyoderma gangrenosum (PG) is a chronic neutrophilic dermatoses characterised by large ulcer healing with cribriform scar. PG can rarely occur over the healed scar. Its diagnosis is dependent upon clinical morphology and exclusion of other diseases. We report an incident of big pyoderma gangrenosum ulcer on a hypertrophic scar since 12 months. Biopsy from ulcer edge was suggestive of PG and hypertrophic scar. The hypertrophic scar had been formed by recovery of a big ulcer 2 years back. The ulcer healed to two-third size over next three months with monthly dexamethasone pulse, day-to-day dental steroid and dapsone. This instance had been unique considering that the PG ulcer had happened over a hypertrophic scar. Such a presentation in PG is rare and doctors should become aware of such occurrence of PG.Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is an unusual but potentially deadly disease caused by dysregulated activation of macrophages against a person’s blood cells. Significant pathologic feature of HLH is hemophagocytosis. We present an incident of HLH complicating methotrexate poisoning in a 65-year-old psoriatic patient with history of renal condition. Diagnosis of HLH was set up as he fulfilled five away from eight HLH diagnostic requirements. This instance report is provided to illuminate clinicians concerning the clinical entity of HLH and also to think and recognize this rare and usually deadly condition in the earliest.Median raphe cyst (MRC) is an uncommon, asymptomatic harmless lesion, which could present anywhere on the midline ridge involving the outside urethral meatus and also the anus. Even though they tend to be developmental in source, they often present in the postpubertal age, aggravated by traumatization, and are also often infected secondarily. MRCs tend to be misdiagnosed as epidermal cysts, steatocystoma multiplex, and eccrine cystadenomas. They are underrecognized much less than ten situation reports occur from the Indian subcontinent. We, herein report a male with an immunohistochemically proven parameatal MRC.Angiokeratomas tend to be variable sized hyperkeratotic vascular papules being characterized histologically by trivial dilated capillaries in papillary dermis with epidermal proliferation. They are able to happen as just one lesion to a generalized form (angiokeratoma corporis diffusum). Angiokeratoma corporis diffusum however initially similar to Anderson Fabry condition, is known to take place in many different lysosomal enzyme inadequacies. We report a case of 22 year old male with angiokeratoma corporis diffusum associated with acroparesthesias, febrile symptoms, sensorineural hearing reduction and renal participation. Histopathological assessment showed characteristic ectatic blood vessels with vacuolated endothelial cells in papillary dermis. On the basis of the clinical assessment and readily available investigations, we suspected him become needing to Anderson fabry disease. Resource limitations restricted our ability to verify our analysis with enzyme assay and electron microscopy. We report this strange instance in desire of re emphasizing the significance of medical assessment for achieving a diagnosis in a reference poor setting.Background Topical corticosteroids (TCs) tend to be widely used for assorted indications in dermatology. But, these can cause an array of symptoms if overused or abused. Topical steroid damaged face is a comparatively new entity which was described in 2008. TC misuse cause a myriad of side effects viz, erythema, telangiectasia, pimples, acneiform eruption, hyper/hypopigmentation, rosacea, and photosensitivity whenever utilized wrongly. Aim The aim of this research would be to determine the prevalence, demographics, and medical presentations of TC abuse on faceamong our population. Materials and techniques This was a cross-sectional study performed at dermatology division of a tertiary attention teaching hospitallocated in eastern India for 12 months. All patients with facial dermatoses attending the outpatient department were inquired about use of TC in immediate past and the ones with good record were included. A detailed clinical evaluation had been undertaken and various demographic and medical information had been recorded. Results A total of 316 patients (53 males, 263 females) served with intrahepatic antibody repertoire topical steroid-induced facial dermatoses throughout the whole study duration. Majority of all of them used these representatives on recommendation of good friends and relatives, pharmacists, tv advertisements, and medical practioners. Mometasone in the form “No-Scar” planning had been the most commonly mistreated topical steroid in our study. The most common side effects experienced were steroid-induced acne (45.2%) or flare of pre-existing zits followed by erythema and telangiectasia (21.2%), hypertrichosis (6.6%), rosacea (2.2%), and atrophy (1.5%). The most common reason behind abusing TC would be to get a fairer skin tone. Conclusion Our study states the clinical habits of TC abused facial dermatoses. The fantasy to get a fairer epidermis one of the individuals of our country features generated the abuse of topical corticosteroids. We conducted this study to create understanding among these patients about the terrible effects of steroid misuse.
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